Case 6: Differential Diagnosis

Build your differential diagnosis: 

Which of these might be the top 4 among your differential diagnosis?
Acute cholecystitis
Correct! Acute onset RUQ pain and tenderness, with jaundice makes cholecystitis possible.

Choledocholithiasis
Correct! Acute onset RUQ pain and jaundice make this possible.

Ascending cholangitis
Less likely. Since the patient is afebrile and hemodynamically stable. Try again!

Acute pancreatitis
Correct! Gallstone pancreatitis may present with RUQ pain and jaundice.

Liver abscess
Less likely. Given the lack of fevers this is unlikely. Try again!

Primary sclerosing cholangitis
Less likely. Given the acuity of presentation and concomitant RUQ pain and tenderness, primary sclerosing cholangitis is unlikely. Try again!

Hepatocellular or Cholangiocarcinoma
Less likely. Given the acuity of presentation and lack of concomitant weight loss, malignancy seems less likely. Try again!

Viral hepatitis
Correct! Given the RUQ pain and jaundice with acute onset, viral hepatitis should be considered. However often patients are febrile.

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